Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway
As a common degenerative disease, osteoarthritis (OA) usually causes disability in the elderly and socioeconomic burden.Previous studies have shown that proper autophagy has a protective effect on OA.Sinensetin (Sin) is a methylated flavonoid derived from citrus fruits.Studies have shown that Sin is a good autophagy inducer and has shown excellent